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The strongest topical anaesthetic concentrations in a unique peel-off cream for fast and effective pain relief.

Prescription Topical Anaesthetic

Pliaglis is a topical local anaesthetic cream that provides safe and effective local dermal analgesia on intact skin prior to superficial dermatological procedures, such as dermal filler injection, pulsed dye laser therapy, facial laser resurfacing and laser-assisted tattoo removal.


Lidocaine and tetracaine (7%/7%) formulation utilizes proprietary phase-changing, topical cream Peel technology.

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Commercial Status


Pliaglis is currently licensed in 39 countries.

Italy, France, Portugal, Spain, China, Mexico, Germany, United Kingdom, Ireland, Switzerland, Brazil, Romania, Belgium, Netherlands, Luxembourg, Saudi Arabia, United Arab Emirates, Kuwait, Oman, Qatar, Bahrain, Jordan, Lebanon, Egypt, Algeria, Morocco, Tunisia, Iraq, Libya, Yemen, Hungary, Bulgaria, Czech Republic, Slovakia, Poland, Russia, Latvia, Lithuania, and Israel.

Crescita is currently looking for a new partner in the USA.

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